Lupus Nephritis Presentation at Pakistan Society for Rheumatology Conference 2019 Pakistan Society for Rheumatology (PSR) Conference 2019 was held in Karachi. Dr. Mohammad Saeed gave a plenary talk on “Lupus Nephritis” and reviewed the pathogenesis and treatment of the disease. This presentation is available for download using the link below. The presentation included kidney…
Read MoreMultiple Sclerosis Pathogenesis Dr. Mohammad Saeed was invited to talk on the “Multiple Sclerosis Pathogenesis” at the Aga Khan University (AKU). The event was organized by the Multiple Sclerosis Research and Education Forum at AKU led by Professor Mohammad Wasay (Neurologist). The day-long Multiple Sclerosis (MS) workshop was part of a nation-wide effort to train…
Read MoreNew Blood Test: PLA2R antibody for Membranous Glomerulonephritis Home Blood Draw / Sample collection: 0334-2121-232 Membranous Glomerulopathy (MG) MG is a morphologic pattern of glomerulonephritis in which immune complexes deposit along the subepithelial aspect of the glomerular basement membrane. The molecular etiology of MG was recently discovered to be Podocyte Phospholipase A2 receptor (PLA2R) and…
Read MoreEarly Arthritis Clinic Many patients have vague joint pains for prolonged durations which only temporarily resolve with anti-inflammatory medications. Such patients are often classified as having Fibromyalgia. However, these patients may actually be suffering from an inflammatory arthritis which needs more focused Rheumatologic treatment (Ref). Recent studies show that patients visit their doctors for…
Read MoreNeuroimmunology Diagnostics Review Abstract Neuroimmunology has led to advanced diagnostics of previously cryptic disorders, using autoantibody testing against neurological targets. Neuropsychiatric syndromes and autoimmune encephalitis can now be routinely diagnosed using specialized antibody tests such as immunofluorescence and immunoblot assays in specialized laboratories. This helps in early and accurate diagnosis, leading to favorable patient prognosis.…
Read MoreNeuroimmunology: Inflammation in the Brain and Nerves The talk is about inflammation and the immune system in general with special focus on the interaction of the immune system with the nervous system. It discusses neurological diseases such as Multiple sclerosis and Autoimmune Encephalitis, their diagnosis with special immunological tests and treatment. Neuroimmunology is the…
Read MoreWhat is ANA? Anti-nuclear antigen. It is a test done to screen for inflammatory diseases such as lupus. 95% patients with lupus have ANA positive. It does not mean that if you have ANA positive you have lupus. This test can be positive in old age or if you have a close relative with…
Read MoreAntibody Tests Rheumatoid factor (RF) One of the most common antibodies tested for. This is present in ~ 70-80% Rheumatoid arthritis (RA) but is also present in other diseases such as hepatitis, chronic liver disease, thyroid disease, certain infections, and other autoimmune diseases like lupus, Sjogren’s etc. Therefore the diagnosis of RA should not…
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